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Abstract -1- IN’I’RODUCTOII MtI am 0’” ’1’BB WORK LipJ.ds consUtut~ part or vital cell structures in addition to baing a major &oUrce of ene.rqy for biologic r4:!actions, their inclusion in the dl4:!tresults in 9reater platability and suppUes a b:i.gn dGln.ll1ty of calories with ~int.al o~~Qlarity and .ininal aoluttl load Csal••, ~989). Lipids have an importan.t rsgu12ltinq role in nQrvous sy$ten via controlling nerve impulse spread and orientat~ Ion owing to their electroinsulatinq properties, tlleyare necessary fm:~synthesis of .any vital subst.ances e.g. p:rocll-t.aqla:ndinpsr,ostaoyolins,leukotil”illlnll’, and lipoxins. which are necessary tor optimal growth, re~roduction, inteqrlty of vari,ous tissues in ”ddition t,o many other functions (~it by .~ .1., 1t85). Since theappuarance at ~Lrly report. or hypercholesterc. lelllla.in the newborns ot knc.wn hypercboloest.erolaeillic p<lrlClnts. interest has heeA focused o~st’Qdie~ of the newborns w1~ the aim ot ~arly detection of a~hercgen!c .~ .. hyp~rlipidemia and a 1arge amount of ~esea~ch and epldealological work bas been devote~ to the stUdy of the sorum lipids patterns in newborn. in an attellpt to define tbo optimal parameters and Bcreenin9 p~oced~res tor early detection and lIlana9Jllontof nyperc:holestorolemia (Ander.oft .ta1., 1971) and Beren”’e;tJlJ.t .1. (19.’1’. -zzn the present ~tudy we estiMated total cholestarOl, lipoprotei’n-cand apolipoprotein-B in C<lrd blood of the . n.avborns at diff,er·ent gestati,onal age. and inneOiborns of diabetic mothers aiming atqivin9 an apprQBche the e:ttects of prenaturity and ma~ernal diabetes on these aspects of lipid tae1:aboHSlDand to the early predictiDn ot hYllerUpide~ ia with its possihle i.pact on tuture as a risk fRctor fDr ath.rosclerosis in o1.de.r .l!.qe. |