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Abstract
Transplantation is one of the greatest achievements of modern medicine with the integration of advances in immunosuppression and surgical techniques. Understanding the anatomy and pathophysiology of the liver and critical care of hepatic patients, all make liver transplantation a widely accepted therapy for patients with end-stage liver disease. The persistent organ shortage and numerous deaths of patients on the waiting list for liver transplantation were the force for the introduction of living donor liver transplantation. Living-donor liver transplantation (LDLT) was first initiated in children. Recently the indicators of LDLT have been extended to adults, especially in countries where the availability of brain-dead donors is severly restricted. The evolution of this modality has expanded its applicability to right lobe donations with good initial results.