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Abstract
The aim of this study is to measure urinary leukotriene E4 levels in patients with bronchial asthma in comparison to control subjects and to define a potential role of Cys LTs in patients with bronchial asthma. The results of this study elucidated that:
1- Pollen was the most common allergen found to cause +ve skin test in patients (63.41% of cases) followed by smoke (53.65%).
2- The mean values of blood eosinophilic percentage, urinary LTE4 and total IgE level of patients were significantly higher than that of control group.
3- The mean values of blood eosinophilic percentage, urinary LTE4 and total IgE level of atopic patients was higher than that of non- atopic patients although the difference was not statistically significant.
4- The mean values of blood eosinophilic percentage, urinary LTE4 and total IgE level were higher in male patients than those of female patients although the difference was not statistically significant.
5- There were positive significant correlations between blood eosinophilic percentage, urinary LTE4 and total IgE level of patients.
6- There were no correlations between age of patients and blood eosinophilic percentage, urinary LTE4 and total IgE level.
7- There were no correlations between duration of illness of patients and blood eosinophilic percentage, urinary LTE4 and total IgE level.
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