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العنوان
The Possible Synergistic Effect of Coenzyme Q10 and N-Acetyl Cystiene Against Liver Cirrhosis Induced by CCL4 Rats /
الناشر
Doaa Mohamed El-Roby Ali,
المؤلف
Ali, Doaa Mohamed El-Roby.
هيئة الاعداد
باحث / Doaa Mohamed El-Roby Ali
مشرف / Laila Mohamed Hassan Fadda
مشرف / Mahmoud Abd El-Aziz
مشرف / Hisham Mahmoud El-Ibiari
الموضوع
Biochemistry. Coenzyme Q10. N-Acetyl Cystiene. Liver Cirrhosis CCL4.
تاريخ النشر
2007 .
عدد الصفحات
147 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة المنيا - كلية الصيدلة - الكيمياء الحيويه
الفهرس
Only 14 pages are availabe for public view

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Abstract

The purpose of the present work is to study the protective effect of CoQ10, which is a vitamin-like substance, and N-acetylcysteine (NAC) against oxidative stress induced by CCl4, and expected synergistic role of the combination of both CoQ10 and N-acetylcysteine (NAC) as hepatoprotective agents by measuring different biochemical parameters. *Serum Samples for measuring: 1-Alanine aminotransferase (ALT) activity. 2- Aspartaye aminotrnsferase (AST) activity. *Plasma samples for measuring : 1-Albumin level. 2- Total billirubin level. 3- Direct billirubin level. 4- Sialic acid level. 5- Nitrite level. * Liver homogenate for measuring : 1- glutathione content. 2-L-ascorbic acid content. 3- Lipid peroxide content. 4- Total protein content.