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Abstract Hospital acquired infections constitue a signifivant medical, social and economic problem. Nosocomial infections have several impacts that affect the patients, the hospitals & the community. There are many different factors that contributed in increased susceptibility to nosocomial infections including the patient, hospital environment and medical care personnel. In this study, 500 nosocomial strains were isolated from hospitalized patients in four educational hospitals; 56.27% were males and 43.73% were females. Of these strains, 49.14% were from urinary tract infections, 24.57% were from diarrheal infections, 15.11% were from wound infections and 11.17% from respiratory tract infections. Rate of nosocomial infection was 57.37%; mixed infection occurred in 33 cases (4.05%). Females were more susceptible to urinary tract infections than males (88.5% and 80% respectively). However, Males revealed higher rates of infection in wound infections (75.4% and 74.07% respectively), respiratory tract infections (38.46% and 33.33% respectively) and diarrheal infections (21.92% and 17.44% respectively). |