الفهرس | Only 14 pages are availabe for public view |
Abstract Aim of the study The purpose of the study is to detect the level of circulating carbohydrate antigens in the serum of active S. haematobium infected patients before and after praziquantel therapy and to correlate it with the intensity of infection as detected by the ovacount/10ml urine. Their value is assessing the efficacy of chemotherapy will be evaluated. Conclusion 1- Detection of circulating carbohydrate antigens is a promising method for diagnosis of active S. haematobium infection avoiding the drawbacks of parasitological methods. 2- Measurement of circulating carbohydrate antigen level may be used as a parameter to intensity of infection and severity of morbidity changes in cases of active S. haematobium infection especially in seroepidemological studies. 3- Circulating carbohydrate antigen detection may be valuable for assessment of efficacy of treatment S. haematobium infection. 4- Praziquantel at a dose of 60ml/kg is more effective in treatment of active S. haematobium infection than 40ml/kg dose. 5- Older age group cleared the circulating antigen more rapidly than younger age group due to difference in immune status. 6- Circulating carbohydrate antigen detection may be valuable in diagnosis of reinfection and persistence of infection with S. haematobium. 7- Cure of S. haematobium infection after PZQ therapy is associated with reduction of liver size and reversal of urinary bladder morbidity changes. |