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العنوان
Chloramphenicol Resistance in Acute Typhoid fever in EL-Minia Province /
الناشر
Taha Mohamed hassanin Mohamed,
المؤلف
Mohamed, Taha Mohamed hassanin
هيئة الاعداد
باحث / طه محمد حسانين محمد
0167816761
مشرف / محمد خيرى النجار
مشرف / زينب أحمد إسماعيل
مشرف / عادل عواد مصطفى
الموضوع
Internal Medicine Acute Typhoid fever Chloramphenicol
تاريخ النشر
1996 .
عدد الصفحات
124 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
1/1/1996
مكان الإجازة
جامعة المنيا - كلية الطب - الأمراض الباطنة
الفهرس
Only 14 pages are availabe for public view

from 142

from 142

Abstract

Aim of the work
To study the incidence of Chloramphenicol failure in treating bacteriologically proved enteric fever cases in EL-Minia province.
Conclusions
1- Chloramphenicol at a dose of 50 Mg/Kg/ day on four divided for 14 day is still of choice in treating patients with acute typhoid fever regarding its many advantages i.e. cheap, available, given orally or parentally.
2- Quinolone (ofloxacin) is very effective alternative treatment to Chloramphenicol in treating Chloramphenicol resistance typhoid fever cases and we can start with it to decrease the duration of therapy (7 days versus 14 days with Chloramphenicol).
3- Widal test at a titre of 1/160 for O and/ or H antigens still of diagnostic importance in typhoid fever keeping in mind that negative or low Widal test is not against the diagnosis of typhoid fever when the disease is clinically suspected.
4- The cut off point at which the Widal titre becomes diagnostic is controversial and this may be due to the differences in the individual populations, salmonella antigens used and the techniques used in each laporatory.
5- Relative bradycardia as well as leucopenia was uncommon features of typhoid fever in typhoid patients being observed in 10% or both.
6- Gurgling coecum is an important physical sign which should be searched for when the disease is suspected in addition to the classic signs: fever, headache, coated tongue, toxic look, tympanitic abdomen, hepatomegaly, abdominal pain and/ or splenomegaly and bronchitic chest.