الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Being the most common primary malignant brain tumors, gliomas represent a challenge for radiological diagnosis and therapeutic management. This partly due to the histological heterogeneity of the lesions and the wide range of differential diagnosis in a significant number of patients.Through the last decades, conventional pre and post contrast MRI sequences proved to be the valuable diagnostic tool for gliomas, yet still inaccuracies and overlap occurred between high and low grades gliomas. Moreover the contrast-enhanced studies actually estimates the degree of blood-brain barrier disruption rather than the inherent tumoral neovascularity, which is well known to correlate positively with malignancy and its grade. This obstacle necessitated the invention of new MRI diagnostic sequences capable of solving these problems. With the introduction of MR spectroscopy and contrast enhanced perfusion imaging, a step towards obtaining radiological base line data, nearly equivalent to the histopathological results was achieved. This study aimed to assess the role of MR spectroscopy and MR perfusion in grading of brain gliomas and included twenty five patients with MRI study suggestive of brain glioma .