الفهرس | Only 14 pages are availabe for public view |
Abstract This work was done to study the macroscopic (endoscopic) changes in the upper gastrointestinal tract in patients with obstructive jaundice. Fourteen patients with obstructive jaundice were chosen from the outpatient clinic and the inpatient word of EL-Minia university hospital. The study showed a high incidence of gastroduodenal mucosal changes in patients with obstructive jaundice as gastritis, erosions, acute gastric ulcer, mucosal hemorrhage and duodenitis. These gastroduodenal mucosal changes in patients with obstructive jaundice accompanied by high serum gastrin level and gastric acid hypertension. According to this study the following conclusions could be reached: 1- Patients with obstructive jaundice are at high risk of development various mucosal gastroduodenal lesions. 2- Gastric mucosal changes are more common than the duodenal mucosal changes, which are the main source of hemorrhages of the upper gastrointestinal tract in patients with obstructive jaundice. 3- About 14% of these lesions were symptomless. In conclusion, patients with obstructive jaundice were at high risk of developing gastroduodenal mucosal lesions throughout the course of the disease. Moreover, those patients may be none sympatomyzing. So, patients with obstructive jaundice should be examined carefully for any manifestations of gastroduodenal troubles. Endoscopy should be apart of the routine investigation of patients with obstructive jaundice to detect and treat various gastroduodenal complications. Moreover, early surgical management to release the obstruction is recommended. |