الفهرس | Only 14 pages are availabe for public view |
Abstract The aim of our work is to study some coagulative & fibrinolytic parameters in neonatal septicaemia and to determine the type of patients in whom the coagulation and fibrinolytic defects occur, and which laboratory test (s) seem to be the most reliable guide to the diagnosis of neonatal septicaemia. In this study we found a significant decrease in W.B.Cs counts in septicemic neonates when compared with normal neonates, while there are no significant changes between the full term and premature neonates. There were significant decreases in platelets count in septicemic neonates when compared with normal neonates, where there were no significant changes between the normal full term and normal premature neonates. There was significant prolongation of P.T. in septicemic neonates when compared with normal neonates; also, there was significant prolongation of P.T. in normal premature when compared with normal full term neonates. There was high significant decrease in coagulation factors (II, V, VII, VIII & X) in septicemic neonates when compared with normal neonates, while there was no significant changes in coagulation factors (II, V, VII, VIII & X) in normal full term neonates when compared with premature neonates. There was significant increase in fibrinogen level in septicaemic neonates when compared with normal neonates, while there were no significant changes between normal full term neonates when compared with normal premature neonates. There was significant of F.D.P in septicemic neonates when compared with normal neonates, while there were no changes between normal full term and premature neonates. As regard E.C.L.T, we found that all full terms neonates had E.C.L.T. more than 2 hours while 20% of premature neonates had E.C.L.T. less than 2 hours and 80% more than 2 hours. In septicemic group was 13% less than 2 hours while that 87% more than 2 hours, where the E.C.L.T. less than 2 hours in septicemic full terms was 11.1% while that in septicemic premature neonates was 15.8%. So, the laboratory tests seem to be the most reliable guide to the diagnosis of neonatal septicaemia are; W.B.Cs count, platelets count, P.T, coagulation factors II, V, VII, VIII & X, fibrinogen and F.D.P. |