الفهرس 
Introduction and Aim of The WorkOnly 14 pages are availabe for public view
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Abstract
Aim of the work
To understand the role of serum and C.S.F. levels of proinflammatory cytokines (TNF, IL-1 and IL-6) and zinc in children with febrile convulsions and cases with encephalitis/ encephalopathy in comparison with normal ranges.
Conclusion
It is concluded that febrile convulsions are the most frequent type of seizures in children under 6 years old. They usually have a good prognosis. Only a few of these children will later suffer from non-febrile seizures. The mechanisms underlying febrile convulsions, which have multiple etiological factors, are not yet clear. Elevated concentrations of the CSF pro-inflammatory cytokines, TNF-α, IL-I β, and IL-6, indicate acute encephalitis/ encephalopathy rather than febrile seizure. However, zinc levels in both serum and CSF decrease in cases with febrile convulsions, which have multiple etiological factors, are not yet clear. Elevated concentrations of the CSF pro-inflammatory cytokines, TNF-α, IL-I β, and IL-6, indicate acute encephalitis/ encephalopathy rather than febrile seizure. However, zinc levels in both serum and CSF decrease in cases with febrile convulsions and elevate in cases with CNS infections. Further studies are required to investigate the role of pro-inflammatory cytokinesand other trace elements in the pathogenesis of convulsive disorders and the relation with CNS infections.