الفهرس 
INTRODUCTION AND AIM OF THE WORKOnly 14 pages are availabe for public view
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Abstract
The aim of this work is to estimate serum level of Zinc, Copper and Calcium in otosclerotic patients, to correlate between any disturbances in these elements occurs with the disease.
The following results and conclusions were obtained:
1- There is significant increase in serum copper level in otosclerotic patients.
2- No statistically significant difference in serum zinc level between otosclerotic patients and control.
3- There is marked decrease in serum calcium level in otosclerotic patients as compared with the control group.
4- There is no correlation between age or sex and concentration of copper, zinc or calcium in the serum of otosclerotic patients. Although the effect of aging and post menopause is not considered because of the certain age group included in the study.
5- No correlation was found between either the duration of the disease or mean air-bone gap in one side and serum concentration of copper, zinc and calcium on the other side which means that the level of the element of the serum of otosclerotic patients has no effect on the severity of the pathologic process.
**Correlating the above mentioned results with the previously recorded results in literature, we can come to the conclusion that the question whether or not metabolic or endocrine disturbances play an essential role in the pathogenesis of otosclerosis must remain open in view of the scarcity and sometimes contradictory data in the literature.