الفهرس | Only 14 pages are availabe for public view |
Abstract Preparation of some phthalazine derivatives chemically related to the hypotensive diug hydralazine. This thesis comprises three main chapters: A svey on the etiology of hypertension d anti— jpertensive agents, discussing their chemical structure and pharmacological activities. Gbapter II Aim of present investigation and theoretical discussion of the experiraen-bal work are presented. pter III Discribs the experimental details of preparing the following 16 nw phthalazine drivatives: 4_Ethyl—l—L ohthalazirrl- (1) thiosemicarbazide ii 4-Isopropyl—l—[ phthalazinylL (1)2 thioseinicarbazide T1 4—Butyl—i— phthalazinyl— (1) 3hioseinicarbazicie IV 4-Cyclohexyl—l—[ phthalazinyl— (i) bhiosemicarbazide V 4-Ailyl—i—phthalazinyi— (1)] thisemicarbazide (32) ‘11 4—Benzyl—i— phthalazinyl— (1)1 thiosemicarbazide 4Pheny1l.... phthalazinyl— (1) thiosemicarbazicle :i 4—Ethyl—i— (i—hydioxyphthalazin--4--yicarbony1) thiosemicarbazide Ghapter I |