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العنوان
Preparation Of Some Phthalazine Derivatives Chemically Related To Hydralazine =
الناشر
Mohamed Gabr Kassem,
المؤلف
Kassem, Mohamed Gabr.
هيئة الاعداد
مشرف / السباعى احمد ابراهيم
مشرف / محمد رجب
باحث / محمد جبر قاسم
مناقش / رافت سامى على
الموضوع
Pharmaceutical Chemistry.
تاريخ النشر
1974 .
عدد الصفحات
61 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/1974
مكان الإجازة
جامعة الاسكندريه - كلية الصيدلة - Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 76

Abstract

Preparation of some phthalazine derivatives chemically related to the hypotensive diug hydralazine.
This thesis comprises three main chapters:
A svey on the etiology of hypertension d anti— jpertensive agents, discussing their chemical structure and pharmacological activities.
Gbapter II
Aim of present investigation and theoretical discussion of the experiraen-bal work are presented.
pter III
Discribs the experimental details of preparing the following 16 nw phthalazine drivatives:
4_Ethyl—l—L ohthalazirrl- (1) thiosemicarbazide
ii 4-Isopropyl—l—[ phthalazinylL (1)2 thioseinicarbazide T1 4—Butyl—i— phthalazinyl— (1) 3hioseinicarbazicie
IV 4-Cyclohexyl—l—[ phthalazinyl— (i) bhiosemicarbazide
V 4-Ailyl—i—phthalazinyi— (1)] thisemicarbazide (32)
‘11 4—Benzyl—i— phthalazinyl— (1)1 thiosemicarbazide 4Pheny1l.... phthalazinyl— (1) thiosemicarbazicle
:i 4—Ethyl—i— (i—hydioxyphthalazin--4--yicarbony1) thiosemicarbazide
Ghapter I