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Abstract In the recent years, stereotactic radiation technique has been widely used more than other radiation techniques due to it is better ability for target localization which associated with less side effects. There are two different type of stereotactic radiation technique either stereotactic radiotherapy (SRT) or stereotactic radiosurgery (SRS). At the beginning, both types are used for diseases rather than tumors like Parkinson’s disease, chronic pain and Epileptic seizures. With deep study for this type of treatment it is become used for treating benign and malignant brain tumors. In the last two years, with science development and also development of different methods which are used for better target imaging and localization, patient immobilization during planning and during radiation therapy sitting and also different treatment planning system which used for calculation of the tumor radiation dose and the dose to the surrounding normal tissue depending on field size, field arrangement, fraction size, total dose, radiation tolerance, radiosensitive/radioresistant nature of the tumor, biologically equivalent dose (BED), detailed dose volume histograms (DVH) of normal tissues and prior radiotherapy. It is started to be used for treating extracranial tumors like bronchogenic and mediastinal tumors, primary unresectable tumors of hepatobiliary tract and hepatic metastasis, primary and metastatic renal tumors, pancreatic tumors, prostatic carcinoma, Head and neck tumors and Spinal, spinal cord and paraspinal tumors. As the era of stereotactic radiation therapy has become in earnest. The advantages of this therapy are easily demonstrated. However we must now show that this advantages leads to improved outcome. So, clinical trials are imperative. In addition, this therapy offers practical advantages that may not be fully appreciated. In the long run, when fully developed, this integrated stereotactic radiation technology will very likely lead to lower cost treatment machines and improved efficiency of planning, delivery and verification, and thus make a valuable contribution to lowering the overall costs of radiation therapy. |