Search In this Thesis
   Search In this Thesis  
العنوان
Chemical Investigation Of Nepeta Argolica :
المؤلف
Ali, Hosam El-Deen Hassan Mohmoud.
هيئة الاعداد
باحث / Hosam El-Deen Hassan Mohmoud Ali
مشرف / Ahmed A. Ahmed
مشرف / Safaa A. El-Moghazy
الموضوع
Agricultural chemicals. Plant regulators.
تاريخ النشر
2004.
عدد الصفحات
174 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الكيمياء
تاريخ الإجازة
1/1/2004
مكان الإجازة
جامعة المنيا - كلية العلوم - Department of Chemistry
الفهرس
Only 14 pages are availabe for public view

from 203

from 203

Abstract

Nowadays, there is a general trend to return back to folk medicine using plant natural products, instead of synthetic drugs, for treating many acquired or genetic diseases to avoid the harmful or sometimes fatal side effects caused by synthetic chemicals.Therefore, this work involved chemical investigation of one species of genus Nepeta.
My interest was isolation and structural elucidation of the constituents of the aerial parts of Nepeta argolica Bory subsp. Argolica with the hope that one or more of these components may find use as a natural medicine. The plants of this genus were used in folk medicine, i.e Nepeta cataria. (catnip), which was recommended as a fortifier, a disinfectant and a cure against cold. Its extract is used in Chinese medicine as antifebril, dropsy, diuretic and also as a remedy for stomach-ache [21].
The extract of Nepeta kopetdaghensis was found to have a bacteriostatic, diuretic and as a cure against eczema-type skin disorders. The biological importance of the members of Nepeta genus prompted me to investigate the aerial parts of N. argolica Bory subsp. Argolica. The fresh plant material of the plant under investigation was collected in Greece, powdered, and extracted with methylene chloride - methanol mixture (1: 1) at room temperature. The extract was fractionated by flash column chromatography on silica gel, then purified on the Sephadex LH- 20 column using different eluting solvents, e.g. n-hexane, methylene chloride and methanol. The structure of the isolated compounds was elucidated by using CI-MS, 1D - NMR CH, l3C and DEPT) and 2D-NMR techniques.