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العنوان
Relationship Of Coronary Flow Reserve To Left Ventricular Function Infarction Size And Angiographic Results After Thrombolytic Therapy /
المؤلف
Ghoneim, Ibtsam Ibrahim EL-Gosoky.
الموضوع
Thrombolytic therapy. Coronary arteries.
تاريخ النشر
2006.
عدد الصفحات
124 p. :
الفهرس
Only 14 pages are availabe for public view

from 139

from 139

Abstract

Although ischemic myocardium must be reperfused if it will be to survive, when a coronary artery is occluded, the issue of preservation of myocardium and left ventricular function following thrombolysis in patients with acute myocardial infarction is complex and the mechanisms involved are multifactorial. Objective: to determine the relationship of the coronary flow reserve to the left ventricular function, infarction size and angiographic results in patients with reperfusion syndrome and those < without reperfusion syndrome after thrombolytic therapy. Methods: The present study includes 50 patients (38 men &12 women) with age ranged
from 28 to 66 years. We divided our patients into two groups according to
the presence or absence of reperfusion syndrome: Group I: Those with reperfusion syndrome (n=20). Group II: Those without reperfusion syndrome (n=30). Results: There was more infarction size as regard:
Number of leads affected: in patients with RS( 45% of patients) with more extensive infarction(more leads are affected) than those without RS(33,3%) but p value not reach the significant value. Total CPK : it was higher in patients with RS than in those without RS with highly significant difference between 2 groups level after (P<O.OOl). Conclusion: CFYR obtained by TTDE is recommended for all patients with acute myocardial infarction as non invasive technique for predicting the regional L Y wall motion, EF, severity of LAD lesion, state of collateral flow and TIMI flow of LAD. Also the study of CFYR obtained by TTDE is recommended in the others coronary vessels. Since the number of cases in the present study was limited, further work is needed on large number of patients to evaluate and support the results of this study.