الفهرس | Only 14 pages are availabe for public view |
Abstract Myasthenia gravis is characterized by weakness and easy fatigability of. skeletal muscle. Incidence of myasthenia gravis is about 1: 10.000 and is highest in women during their third decade. In men, it is typically presented in the sixth and seventh decades.Myasthenia gravis is a neurological autoimmune disease. It is characterized by muscle weakness that progressively worsens on repetition but improves by rest.Myasthenia gravis is a disease of great significance for the anesthesiologist, because it affects the neuromuscular junction.Neuromuscular disorders are relatively uncommon. Patients present to the operating room with some regularity for diagnostic studies, for treatment of complications, or for surgical management of unrelated disorders.Diminished respiratory muscle strength and enhanced sensitivity to muscle relaxants predispose these patients to post operative ventilatory failure. A basic understanding of the major disorders and their potential interaction with anesthetic agents is necessary to avoid post operative morbidity of this nature. |