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Abstract
In response to pathogen exposure, a host employs both the innate and adaptive arms of the immune system to protect against infection. The innate immune response utilizes both physical barriers such as skin and mucosal epithelium as a means of avoiling infection and rapid cellular responses enacted by dendritic cells (DC), monocytes, natural killer cells, granulocytes, and epthelial cells to protect a newly infected host. These cells express pattenrn recognition receptors that mediate responses to pathogen-associated molecular (PAMP) that are conserved among microorganisms.