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Abstract
This work was done in Rheumatology and Rehabilitation, and
Biochemistry Departments of Zagazig University Hospitals to evaluate the
relation of the level of total serum adenosine deaminase to the disease
activity in SLE and RA.
This study comprised a total of 65 subjects. They were divided into 3
groups:
1- Group I: included 25 patients suffering from RA.
2- Group II: Included 25 patients suffering from SLE.
3- Group Ill: Included 15 normal volunteers.
All cases were subjected to careful clinical examination and
laboratory investigations including:
1- Complete blood picture.
2- Erythrocyte sedimentation rate.
3- C- reactive protein.
4- Rheumatiod factor.
5- 24 hrs urine protein.
6- Liver and kidney function tests.
7- Anti-ds DNA titre.
8- Serum total adenosine deaminase activity.
The following results were obtained:
1- A highly significant elevation of serum ADA in active SLE patients
compared to inactive patients.