الفهرس 
contentsOnly 14 pages are availabe for public view
 |  | from | 157 |  |  |
| | | from | 157 | | |
Abstract
In the present work the author synthesized several B-ca.ffeine acid hydrazides together with some of their derivatives, as well as derivatives of 8-caffeine carboxy¬aldehyde to be tested for their antituberculous activity. The bacteriological investigations had showed that 8¬caffeineacetic acid hydrazide in 0.5% concentration is a more potent tuberculostat than isoniazid, streptomycin, and PA.S, using M. tubercle bacilli strain isolated from hospitalized patients in A.R.E.
The thesis includes the following four chapters: I... J:ntroduct~
This consists of four parts.
1- Occurrence and relationships of caffeine to other purines. 2- Properties of caffeine. 3- Studies on 8-subs-tituted caffeine derivatives. 4- Ohemotherapy of tuberculosis. 11- Aim of The Present InyestiE;ation
The auth.or illustrates in this chapter the micro¬biological and pharmacological basis of the present work and gives a scheme for the preparation of the new final suggested compounds.