الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
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sU’~y ..uruCOBCLUSIQN
Rhinoscleroma is nJt uncommon in ~pt. It is
mvr •• prevalent in certain ar’;as. Saarlda is one of
these endemic areas •
It is more common among pUJr classes • The aetiology
has aruused much contruversy. It is now gene~
rally accepted that the disease is due to infection
by Klebsiella rhinoacleromatia ,
The bacillus can be isulated frum nearly every
patients • It disap~eara with clinical cure .Lastly
animal inoculation haa been reported to reproduce
scleroma like lesions and the organism could be rec’.
lveredtrom the experllll:ntallesion • The organism
can ~ isolated from ~atienta either by taking a
nasal swabs or examination a piece of tissue.
The organism can be cultured on bloud agar or
chololate agar •
Many antibiotic have been tried in the treatment
of rhinoscleroma •
The m.lst commonly used drugs are the following:-
I) Strepto~cin:
On in vitro sensit~vity teat. it is found that
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the organism shuws variable de6ree of sensitivity
( highly and moderately sensitive ) alsu in vivo
it gives variable de~ee of healing with great tendency
to reccurrance •
Moreover streptomycin is tuxic to 8 th cranial
nerve.
The organisIllBare less sensitive to I. N • .d.
and resistant to ~, A. S.
Hovrever it was fUWld that r, Ii• .d. &~. A. S.
when given in c<)ll1binatiunwith streptum,ycin enhances
its effect un A.rhinoscleromatis and de~aY
thl:ldevelopment or _oiI1st8l1~ stft:1D8 ’to it •
J) Aueromycin and Kanamycin :
They showed gUJd effects on Klebsiella rhinoscleromatis
in vitro but in vivu they were efftdctive
especially in early stages of disease in late
stages they appeared valueless •
Aueromycin used locally as 0iDt~nt •
Attia ( 1957 ) was repurted to be of value especially
in cases with tdxcessive nasal scabing.
I
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4) Ri1’amJ:’Cin( R1mactane ) :
A. Ali &: co-worlu:lrs ( I900 trying rimactane in
treatment of r.Jinoscleroma fOWldthat in vitro
Klebsiella rhinoscleromatis waS inhibited in zone
about I2 I8 Mm. di~ter • They got 92 % cure
01’ cases compar\;ldto eo % in cases 01’ streptolll,ycin •