الفهرس 
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Abstract
Aim of The Work
This work aimed at study the relation between serum ghrelin levels and epilepsy either generalized or partial, and the effect of therapy with valproate on serum ghrelin levels in epileptic patients.
Our study showed:
• Significant statistical differences regarding serum levels of ghrelin being elevated in all epileptic patients when compared to controls.
• Significant statistical differences regarding serum levels of ghrelin being elevated in patients with partial epilepsy when compared to patients with generalized epilepsy.
• Serum levels of ghrelin were increased in epileptic patients received valproate therapy when compared to those not received treatment. However the differences were not significant.
• In the studied groups of epileptic patients received valproate treatment we found statistically significant differences in serum levels of ghrelin being elevated in patients with controlled epilepsy when compared to patients with uncontrolled epilepsy. We also found significant Significant inverse correlation between ghrelin level and BMI.
Conclusion
From the present study we concluded the following:
1. Serum ghrelin level increased in all patients with epilepsy.
2. Serum ghrelin level increased in patients with partial epilepsy than in patients with generalized epilepsy.
3. Valproate therapy induces weight gain and associated with higher serum ghrelin levels than patients not receive treatment.
Recommendations
Further evaluation for hormonal studies to know the effect of epilepsy on hormones and the effect of hormones on epilepsy.