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Abstract
Chlamydia pneumoniae is a human pathogen recognized as an important cause of respiratory illness. Its spread is by person to person transmission via respiratory droplets. Approximately (55.8%) of adult populations around the world have antibodies to C. pneumoniae, which suggests that the infection is extraordinary prevalent and reinfection is common.
Chlamydiae are highly complex microorganisms which posses a number of different antigens such as genus specific antigens, and type specific antigens.
The present study aimed to detect C. pneumoniae infection in patients with acute respiratory tract infection by three methods: the cell culture and PCR for detection of C. pneumoniae antigen, the indirect micro-immunofluorescence for detection of C. pneumoniae antibodies, and compare between them to detect which of them was more sensitive and specific for diagnosis of chlamydia pneumoniae infection.
This study included 50 subjects, were divided into 2 main groups:
group I (The control group): included 10 apparently healthy volunteers, with age range (22-55) years old,