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Abstract The work presented in this thesis represents a phytochemical investigation of three Amaryllidaceae plants, namely, Hymenocallis littoralis Salisb., Narcissus pseudonarcissus and Narcissus cv. Breath of Spring. This thesis consists of six parts: Part I- Screening of the studied plants for: a- Acetylcholinesterase Inhibitory alkaloids using Thin Layer Chromatography in combination with bioactivity staining b- Flavonoial constituents In view of the potential use of plants for the discovery of new acetylcholineserase inhibitors, an in-situ TLC autobiographic method was employed on the different organs of the fresh plants of Narcissus cv. Breath of Spring, Narcissus pseudonarcissus and Hymenocallis littoralis Salisb. collected in the flowering stage using the method outlined by Rhee et al. and was used for preliminary screening of extracts and fractions for compounds with AChE inhibitory effects. As a result of bioactivity-directed fractionation of the extracts of the studied plants, the chloroform extracts of their bulbs were selected for further phytochemical investigation which . |