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Abstract
Nowadays, large number of factories and industrial companies are established near and on side of the Nile their tnbutaries.Eflfuents, of a considerable bluk, of such factories are poured in to the fresh water habitat. Consequently, aquatic organisms especially the edible ones and in particu]ar fishes are liable to such waters polluted with heavy metals and other contaminants.
The Nile tilapia (Oreochromis niloticus) is the most widely distributed natural and cultural fish in the tropical and subtropical areas of the world including Egypt. This fish is the most increasingly consumed one in those areas, therefore it is a suitable model for studying the distribution of heavy metals in different organs and tissues of the fish.
Therefore, the present investigation aim was to determine the possible toxicological effect on different biological, biochemical and histopathological aspects of fish Oreochromis niloticus exposure to sublethal concentration of heavy metal (copper and cadmium) at levels of 1/8, 1/16 and 1/32 LC5O of copper and 1/16, 1/32 and 1/64 LC5O of cadmium.
The study also conducted with determing and measuring the amount of the tow metals accumulated or deposited in each of the studied organs liver, kidney, gills and muscle).