Search In this Thesis
   Search In this Thesis  
العنوان
Role of cisplatin containing regimens in treatment of NSCLC with special emphasis on nephrotoxicity/
الناشر
Alex uni F.O.Medicine ,
المؤلف
Mostafa ، Dina Anwar.
هيئة الاعداد
باحث / دينا أنور مصطفى
مشرف / سعــــــــيد النويعـــــــم
مشرف / نشات سعد لطفى شحاته
مشرف / شعبان محمد عبد الرحمن العسال
الموضوع
Clinical Oncology and nuclear medicine.
تاريخ النشر
2005 .
عدد الصفحات
p126.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأورام
تاريخ الإجازة
1/1/2005
مكان الإجازة
جامعة الاسكندريه - كلية الطب - علاج الأورام والطب النووى
الفهرس
Only 14 pages are availabe for public view

from 131

from 131

Abstract

the present study has the following objectives to evaluation of cisplatin nephrotoxicity in these patients by dynamic radionuclide renography.
This study included 30 patients with NSCL;C seen in nthye clinical oncology department between June2004 to June2005.
All patients received at least 3 cycles of cisplatin (75mg/m2 ) containing regimen either as a part of adjuvant therapy or sequential chemotherapy or palliative chemotherapy approach.
The diagnostic work up included history taking, physical examination, complete blood picture, liver and kidney functions , chest x-ray , C.T chest , U/S abdomen , renal imaging with radionuclides.
Assessment of GFR by radionuclide studies was superior to biochemical tests in detecting renal impairment.
Only one patient suffered grade 2 nephrotoxicity , otherwise good hydration helped in minimizing the cisplatin nephrotoxicity.