الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
The aim of this study was to evaluate the effects of medical treatment versus medical treatment with mild hypothermia (340C) in patients with moderate head injury. The evaluation was done clinically by Glasgow Coma scale score (GCS) and laboratory by the changes in IL-1 _β, IL-6, Tumor necrosis factor-alpha (TNF- alpha) and S-100 β protein.
Conclusions:
1- The present study has demonstrated that mild therapeutic hypothermia (34oC) for 24 hours has suppressed the increased arterial and venous IL-6 and this suppression sustained even after the rewarming period.
2- Mild therapeutic hypothermia has not affect the release of IL-β, TNF-alpha or S 100 β protein and this may be due to the late application of hypothermia and the shorter duration of cooling or may be due to the early release of these substances after traumatic brain injury so the peak levels was missed before the application of hypothermia.
3- The present study has demonstrated that mild hypothermia did not affect the neurological outcome.
Recommendations:
1- Further studies must be done to evaluate the optimal duration of cooling and the optimal effective temperature for patients head injury.
2- Early application of hypothermia as early as possible after traumatic brain injury.