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العنوان
Electron Microscopic Changes in Basal Cell Carcinoma Treated by Ndyag Laser Hyperthermia /
الناشر
Ghada ali Nasif Mohamed ,
المؤلف
Mohamed, Ghada ali Nasif
هيئة الاعداد
باحث / Ghada Ali Nasif Mohamed
مشرف / Mohamed Hany El-Tonsy
مشرف / Mostafa Mokhtar Kamel
مشرف / Jouni Uitto
مشرف / Fatma Yousef Saleh
الموضوع
Dermatology, STDs & Andrology Basal Cell Carcinoma
تاريخ النشر
2007 .
عدد الصفحات
212 p.
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأمراض الجلدية
تاريخ الإجازة
1/1/2007
مكان الإجازة
جامعة المنيا - كلية الطب - Dermatology, STDs and Andrology
الفهرس
Only 14 pages are availabe for public view

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Abstract

The present study is concerned with the effect of ND-YAG laser hyperthermia on basal cell carcinoma as a new modality aiming at decreasing the amount of scattered extra heat to the normal surrounding issues and thus achieving the best treatment results with best cosmetic appearance.
The procedure consisted of treating the target lesion with ND-YAG laser hypothermia is segmental manner in clockwise direction using a test segment in the first session. After we reached 41C in BCC lesions, temperature was maintained at that range for at least 30 seconds to one minute.
Evaluation of Nd-YAG laser hyperthermia in treatment of malignant skin tumors was based on cure rates after laser hyperthermia But in the present study the evaluation was based on clinical, histopathological and by electron microscope.
Nd-YAG laser hyperthermia showed excellent results in 36 cases (90%) of BCC patients, and failed to cure 4 (10%) of BCC patients.
In conclusion, Nd-YAG laser hyperthermia proved to be effective in treatment of basal cell carcinoma, it could be recommended as a treatment modality. The most important advantage of ND-YAG laser hypothermia is the extreme localization of heat directly to the lesions that led to the excellent cosmetic result in treatment of these tumours. Many treatment modalities showed excellent cure rates but most of these modalities did not show excellent cosmetic result in comparison to ND-YAG laser hypothermia. ND-YAG laser hypothermia is an easy, bloodless, non-invasive technique that was performed in outpatient clinic.
Patients tolerated the procedure easily and needed no local anaesthesia.
We recommend using of ND-YAG laser hypothermia in treatment of BCC especially in old age as some patients may be at risk of surgical intervention. We also recommend using electron microscopic examination as a method of evaluation for the cure as histopathologically free patients may still have remmants of malignant cell not shown except in EM examination.