الفهرس 
Introduction and Aim of the WorkOnly 14 pages are availabe for public view
 |  | from | 290 |  |  |
| | | from | 290 | | |
Abstract
the present study aimed at evaluation of apoptosis, proliferation as well as p53 and bcl-2 protein expression in all examined tumors together with evaluation of their inter-relationships as well as their relationships with other clinicopathologic variables including age , sex of patients, site, size , growth pattern of tumors , histoologic subtypes of adenomas or carcinomas in addition to grade of dysplasia ( in adenomas) or degree of differentiation, Dukes` stage, regional lymph node metastasis and ALL ( in carcinomas ). the present study has demonstrated the following points: 1- apoptosis and proliferation are closely related processes suggesting common regulatory mechanisms or compensatory mechanisms for both events. Alterations in both processes play important roles in the colorectal carcinogenesis. 2- AI may be of prognostic value in colorectal carcinoma being associated with cancer grade.