الفهرس 
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Abstract
Heterocyclic annelated pyridazines continue to attract considerable attention which mainly arises from the large variety of interesting pharmacological activities observed with pyridazine derivatives. The recent discovery of a natural antifungal antibiotic containing this heteroarene system (Pyridazinomycin) most probably will stimulate even broader interest in 1,2-diazine chemistry. In connection with these facts and my interest in the synthetic potential of fused pyridazine systems, the purpose of the present study was to synthesize a series of them for pharmacological evaluation.
The objective of this study are:
1- The first part of this work was concerned with the photolysis of 3-diazo-4,5-diphenylpyrazolo[3,4-c]pyridazine in different reagents.
2- In the second part of this investigation, the photochemical reactions of 3-azido-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine in different reagents was studied.
3- The third part of this work was concerned with the synthesis of 3-hydrazino-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and study its reactions with different reagents.
4- To investigate any mechanistic information which may be generated during the course of this work.
5- Extension of the synthetic scope of these reactions are under study.
Heterocyclic annelated pyridazines continue to attract considerable attention which mainly arises from the large variety of interesting pharmacological activities observed with pyridazine derivatives. The recent discovery of a natural antifungal antibiotic containing this heteroarene system (Pyridazinomycin) most probably will stimulate even broader interest in 1,2-diazine chemistry. In connection with these facts and my interest in the synthetic potential of fused pyridazine systems, the purpose of the present study was to synthesize a series of them for pharmacological evaluation.
The objective of this study are:
1- The first part of this work was concerned with the photolysis of 3-diazo-4,5-diphenylpyrazolo[3,4-c]pyridazine in different reagents.
2- In the second part of this investigation, the photochemical reactions of 3-azido-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine in different reagents was studied.
3- The third part of this work was concerned with the synthesis of 3-hydrazino-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and study its reactions with different reagents.
4- To investigate any mechanistic information which may be generated during the course of this work.
5- Extension of the synthetic scope of these reactions are under study.
Heterocyclic annelated pyridazines continue to attract considerable attention which mainly arises from the large variety of interesting pharmacological activities observed with pyridazine derivatives. The recent discovery of a natural antifungal antibiotic containing this heteroarene system (Pyridazinomycin) most probably will stimulate even broader interest in 1,2-diazine chemistry. In connection with these facts and my interest in the synthetic potential of fused pyridazine systems, the purpose of the present study was to synthesize a series of them for pharmacological evaluation.
The objective of this study are:
1- The first part of this work was concerned with the photolysis of 3-diazo-4,5-diphenylpyrazolo[3,4-c]pyridazine in different reagents.
2- In the second part of this investigation, the photochemical reactions of 3-azido-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine in different reagents was studied.
3- The third part of this work was concerned with the synthesis of 3-hydrazino-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and study its reactions with different reagents.
4- To investigate any mechanistic information which may be generated during the course of this work.
5- Extension of the synthetic scope of these reactions are under study.
Heterocyclic annelated pyridazines continue to attract considerable attention which mainly arises from the large variety of interesting pharmacological activities observed with pyridazine derivatives. The recent discovery of a natural antifungal antibiotic containing this heteroarene system (Pyridazinomycin) most probably will stimulate even broader interest in 1,2-diazine chemistry. In connection with these facts and my interest in the synthetic potential of fused pyridazine systems, the purpose of the present study was to synthesize a series of them for pharmacological evaluation.
The objective of this study are:
1- The first part of this work was concerned with the photolysis of 3-diazo-4,5-diphenylpyrazolo[3,4-c]pyridazine in different reagents.
2- In the second part of this investigation, the photochemical reactions of 3-azido-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine in different reagents was studied.
3- The third part of this work was concerned with the synthesis of 3-hydrazino-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and study its reactions with different reagents.
4- To investigate any mechanistic information which may be generated during the course of this work.
5- Extension of the synthetic scope of these reactions are under study.
Heterocyclic annelated pyridazines continue to attract considerable attention which mainly arises from the large variety of interesting pharmacological activities observed with pyridazine derivatives. The recent discovery of a natural antifungal antibiotic containing this heteroarene system (Pyridazinomycin) most probably will stimulate even broader interest in 1,2-diazine chemistry. In connection with these facts and my interest in the synthetic potential of fused pyridazine systems, the purpose of the present study was to synthesize a series of them for pharmacological evaluation.
The objective of this study are:
1- The first part of this work was concerned with the photolysis of 3-diazo-4,5-diphenylpyrazolo[3,4-c]pyridazine in different reagents.
2- In the second part of this investigation, the photochemical reactions of 3-azido-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine in different reagents was studied.
3- The third part of this work was concerned with the synthesis of 3-hydrazino-4,5-diphenyl-1H-pyrazolo[3,4-c]pyridazine and study its reactions with different reagents.
4- To investigate any mechanistic information which may be generated during the course of this work.
5- Extension of the synthetic scope of these reactions are under study.