الفهرس Only 14 pages are availabe for public view
 |  | from | 61 |  |  |
| | | from | 61 | | |
Abstract
Prostaglandins of the E series produce strong uterine contractions and therefore have been widely used for the induction of labor in late pregnancy, as abortifacient agents in early pregnancy and recently in augmentation of labor in late pregnancy.
The use of natural prostaglandins has been limited by their instability, high cost, rapid metabolism and high incidence of gastrointestinal side effects. Oxytocin is the one mostly used for induction of labor, its augmentation and management of the third stage of labor.
Misoprostol (Cytotec®) is a synthetic FQE1 analogue and is as effective as oxytocin in augmentation of labor. Misoprostol is not expensive, safe and simple to administer as it is placed in the vagina or given orally. Limited data are available about the evaluation of its use in augmentation of labor in primigravidae.
The aim of this study was to evaluate the efficacy, safety and compliance of misoprostol in augmentation of labor in primigravidae, and evaluation of its side effects on the.mother and fetus and its comparison with the commonly used oxytocin.