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Abstract
The present study conducted on 20 subjects after successful kidney transplantation randomly selected from Nasser Institute for Search & Treatment.
All patient were subjected to :
Full medical history and clinical examination with stressing on duration of renal transplantation, medications, complications, any associated diseases and important osteoprosis risk factors like age, gender, duration of dialysis, cumulative prednisone dose, smoking and diabetes.
Routine laboratory investigation, liver function tests, CBC, renal function tests, serum albumin and complete urine analysis.
Serial assessment of serum alkaline phosphatase, serum calcium, serum phosphorus, serum parathyroid hormone (PTH) and serum osteocalcin.
Bone mineral density (BMD) measured by dual energy X-ray absorptiometry (DEXA).
Non of patients had diabetes, neoplasia, liver disease, cashexia or had been previously parathyroidectomy.
To study bone turnover following renal transplantation, the subjects were divided into two groups, (group A) included 10 patients in the earlier post transplantation period, up to 1 year, (group B) included 10 patients more than 1 year postrenal transplantation
Comparison between group A and group B, showed non significant difference in SGPT, Hb, Cr, Alb, PO4, Ca++, Alk. Phosphates, Osteocalcin and DEXA.