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Abstract
The present work was carried out to study the efficacy of
florfenicol (30 mg/kg b. wt.) and its combination at 15 mg/kg b. wt
with streptomycin 50 mg/kg b. wt against experimentally Salmonella
pullorum infected chickens. Another goal was to study the side effects
that could be reflected on liver and kidney functions and the
histopathological changes involving the vital organs.
I. Efficacy of therapeutic regimen of florfenicol and its
combination with streptomycin in chickens experimentally
infected with Salmonella pulllorum:
Chickens experimentally infected with Salmonella pullorum and
non treated showed severe clinical signs (depression, loss of appetite,
ruffled feathers and chalky white diarrhea around the vent)
Treatment with florfenicol alone resulted in complete
disappearance of clinical signs while treatment with its combination
with streptomycin reduced the symptoms.
11.Effect of florfenicol and its combination with streptomycin on
blood constituents of chickens:
l-Healthy chickens treated either with florfenicol alone or in
combination with streptomycin displayed non significant decrease
in erythrocytic count, hemoglobin concentration and packed cell
volume.