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العنوان
Molecular Genetics Studies of Some Developmental Abnormalities in Wild Mice =
الناشر
Abeer Fikry El-Nahas ;
المؤلف
El-Nahas, Abeer Fikry
هيئة الاعداد
مشرف / سعيد عبد المنعم الفقى
مشرف / عادل محمد المصرى
مناقش / يوسف صلاح الدين غانم
مناقش / محمد عبد البارى مندور
باحث / عبير فكرى السيد النحاس
الموضوع
GENETICS Genetics .
تاريخ النشر
2001 .
عدد الصفحات
140 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
البيطري
الناشر
Abeer Fikry El-Nahas ;
تاريخ الإجازة
25/09/2001
مكان الإجازة
جامعة الاسكندريه - كلية الطب البيطرى - رعاية الحيوان
الفهرس
Only 14 pages are availabe for public view

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from 141

Abstract

The present work aims to throw light on the effect of the combination between one of Kit mutations (Kit and other Kit alleles originated from wild mice as KItM allele from Japanese wild mice (MOG) or Kits allele from Mus m. musculus (NJL) on the fertility of these mice. This work based on the fact that, the combination between Kitw allele and Kits allele from Spanish wild mice (Mus spretus) lead to sterility of the males.
This study was carried out through:
I. Congenic mice strain.
The mice were obtained and maintained as inbred strains at the laboratory on Hokkaido
University in Japan. The wild mice were used for construction of two-congenic mice strains using inbred laboratory mice (C57BL) as background.
However, this study was carried out by:
II. Simple sequence length polymorphism (SSLP):
For mapping of MOO and NJL Kit allele on chromosome 5 of
C57BL. To detect which part of chromosomal region adjacent to Kit
locus derived from MOO or NJL in the two-congenic strains. til. Nucleotide sequence of Kit eDNA
IlL a. From C578L compared with that of Balb/C
III. b. From MOO compared with that of C57BL.