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Abstract We presented 85 patients with SSNHL and idiopathic tinnitus who under want treatment with ozone therapy to be compared with controlled placebo groups. We depended upon multiple mechanisms of ozone action that proposed to overcome the pathogenesis of ozone action that proposed to overcome the pathogenesis of SSNHL and idiopathic tinnitus. It was reported that ozone possesses an antiviral activity, vasodilator effect, promotion of increasing the oxygenation of ischemic tissues as well as immune modulatory effect. We used the most popular method of ozone administration which was the major auto-hermotherapy with a total of ten sessions for both idiopathic SSNHL group and idiopathic tinnitus group. We have shown that our treatment protocol by ozone therapy succeeded in treating patients with SSNHL with a significant success rate of about 77% in comparison to placebo (40%). On the other hand, ozone therapy has failed to treat patients with idiopathic tinnitus. |