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العنوان
CLOPIDOGREL AS ADJUNCTIVE REPERFUSION THERAPY TO THROMBOLYTIC THERAPY IN MYOCARDIAL INFARCTION/
الناشر
Ain Shams University. Faculty of Medicine. Department of Cardiology,
المؤلف
Milad, Ashraf Alfi
هيئة الاعداد
باحث / Ashraf Alfi Milad
مشرف / Samir Saleh Wafa
مشرف / Sameh Saleh Thabet
تاريخ النشر
2008 .
عدد الصفحات
106 p.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2008
مكان الإجازة
جامعة عين شمس - كلية الطب - Cardiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Acute myocardial infarction is one of the leading causes of death worldwide. Occlusive thrombus in the absence of significant collateral vessels most often results in acute ST-segment elevation Myocardial infarction (STEMI) (Deepak p.Vive Kananthan and Micheal A. Lauer). The use of thrombolysis recanalyzes the thrombotic occlusion by lysing the fibrin-rich elements, resulting in restoration of coronary blood flow. Streptokinase (SK) is a reasonable alternative to 2nd or 3rd generation agents (Alteplase tpa, Reteplase) Mark et al. Clopidogrel (Plavix) is an antiplatelet aggregation which acts by inhibiting ADP-induced platelet activation (selective antagonism). It is indicated for the reduction of the atherosclerotic events (MI, stroke, vascular death) in patients with atherosclerosis documented by recent stroke (CAPRIE study 1996).